Rheumatoid serodiagnosis is possible through correlation of results obtained from patient serum to the RA, CRP and ASO tests.

ASO Latex Kit: Detection of ASO in serum may aid in the diagnosis of streptococcal infections. Infections caused by acute Streptococcal infection result in the production of anti-streptolysin O antibodies due to the presence of the streptolysin O antigen liberated by the bacteria. Information on the extent and degree of infection can be obtained from the measurement of serum ASO levels. Increased ASO levels are also associated with rheumatic fever and glomerulonephritis.

RF Latex Kit: Rheumatoid factors (RF) are a group of IgM antibodies directed against antigenic sites on the body’s own IgG antibodies. Between 60 and 80% of patients with rheumatoid arthritis (RA) possess this abnormal protein in their blood and joint fluid. Detection of RF is therefore of value in the diagnosis and monitoring of the disease.

CRP Latex Kit: CRP (C-reactive protein) is a serum constituent originally defined by its ability to precipitate Pneumococcus C polysaccharide. Characteristically, CRP appears in the serum of individuals in response to various inflammatory conditions and tissue necrosis, and disappears as the causative conditions subside. CRP is routinely found in cases of bacterial infection, active rheumatic fever and many malignant diseases, and is often seen in association with cases of rheumatoid arthritis, viral infections and tuberculosis. CRP has also been detected in patients following blood transfusions and surgical operations as well as in patients with burns, pemphigus vulgaris and other bullaous lesions.

IM Latex Kit: The IM latex kit is a latex agglutination slide test for the qualitative and semi-quantitative determination of infectious mononucleosis in undiluted serum or plasma. The reagent used is a suspension of polystyrene latex particles which have been coated with partially purified glycoprotein from bovine red blood cells. The heterophile antibody associated with IM binds to the corresponding antigenic determinants on the coated latex forming visible macroagglutination.

sLE Latex Kit: This is a latex agglutination slide test for the qualitative and semi-quantitative determination of anti-deoxyribonucleic protein (DNP) associated with systemic lupus erythematosis in human serum. Latex particles are bound with native DNP by means of an intermediary albumin matrix. These coated particles combine with anti-DNP antibodies in serum to give visible agglutination.


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