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MELARIS®
MELARIS®
Overview
How to Order
Testing for Hereditary Melanoma
What is MELARIS
®
?
MELARIS
®
assesses an individual's risk of developing melanoma, based on the detection of mutations in the p16 gene.
What is the test?
MELARIS
®
is a genetic test that requires only a small blood sample to determine if a patient has a p16 gene mutation,
indicating a predisposition for melanoma. This is the most accurate clinical test available to detect p16 gene mutations.
Why choose MELARIS
®
?
MELARIS
®
genetic testing enables the clinician to:
Take a proactive management approach with clearly identified at-risk patients
Avoid unnecessary interventions in family members who have not inherited a known familial mutation
Target increased surveillance and other interventions to individuals with a p16 mutation – maximising patient care while increasing clinical efficiency
Counsel patients and family members on the underlying cause of cancer, in the case of a positive result. Significantly improve patient outcomes.
How can I order MELARIS
®
from Lab21?
MELARIS
®
testing requires a blood sample, and it can only be requested by a medical doctor. To request MELARIS
®
testing service, simply contact the dedicated Lab21 Customer Services Team.
The turnaround time is 21 working days from the receipt of the sample at Lab21. A rapid option with 12-day turnaround time is also available.
References
Beaudet AL, Tsui LC. A suggested nomenclature for designating mutations.
Hum Mut
1993; 2:245-248
Burden et al. Genetic and environmental influences in the development of multiple primary melanoma.
Arch Dermatol
, 1999; 135: 261-265.
Greene. The genetics of hereditary melanoma and nevi. 1998 update.
Cancer
, 1999; 86: 2464-2477.
Hayward. New developments in melanoma genetics.
Curr Oncol Rep
, 2000; 2: 300-306.
Myriad and MELARIS are either trademarks or registered trademarks of Myriad Genetics, Inc in the United States and other jurisdictions.
MELARIS
®
Service
Lab21 Customer Services
Phone:
+44 (0)1223 395450
Email:
info@lab21.com
To order MELARIS
®
, your first point of contact is the dedicated Lab21 Customer Services Team who handles:
Test Requests and Customer Support
Sample logistics from Customer to Lab21
Forwarding of sample to Myriad Genetics, US, for testing
Reporting of the Results
The MELARIS
®
options from Lab21 are:
Comprehensive MELARIS
®
: Comprehensive analysis of p16 (CDKN2A) gene mutations
Single Site MELARIS
®
: Analysis of a single, known p16 (CDKN2A) gene mutation
Testing is performed at the CLIA and CAP accredited Myriad Genetic Laboratories. All mutations and genetic variants are named according to the convention of Beaudet and Tsui.
The turnaround time is 21 working days from receipt of sample at Lab21. A rapid option with 12-day turnaround time is also available for both the Comprehensive and Single Site MELARIS
®
mutation test.
Myriad and MELARIS are either trademarks or registered trademarks of Myriad Genetics, Inc in the United States and other jurisdictions.
Download Here
MELARIS
®
Advice Sheet
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